Reduced Representation Bisulfite Sequencing (RRBS) is a high-throughput method for methylome analysis combines enzymаtic restriction and bisulfite sequencing in order to enrich sample for the areas of the genome that have a high CpG content. This method allows analyzing the levels of methylation at single CpG-dinucleotides and detecting specific methylation patterns. Moreover, RRBS is a highly sensitive method, which is also valid for examinations of clinical specimens. RRBS technique reveals more than 5 million of CpG-sites in whole genome scale, 65-75% of which has coverage over x10.
CpG islands methylation analysis, comparative analysis of genome methylation.
From $ 630 per sample. Prices are available on request.